A heavy-wall steel having a flange thickness of about 40 mm or more and possessing excellent strength, toughness, weldability, and seismic resistance capable of being used for structure members such as columns and beams of high-rise buildings. The heavy-wall steel has a tensile strength of about 490-690 MPa, a yield ratio of about 80% or less, and Charpy absorbed energy at 0.degree. C. of about 27 J or more at the center in terms of thickness of the flange portion in each of the rolling direction, the direction perpendicular to the rolling direction, and the plate-thickness direction.