发明授权
- 专利标题: Methods and pharmaceutical compositions for oral delivery of molecular iodine
- 专利标题(中): 口服分子碘的方法和药物组合物
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申请号: US960149申请日: 1997-10-29
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公开(公告)号: US5885592A公开(公告)日: 1999-03-23
- 发明人: Yongjun Duan , John Hickey , Rick Panicucci , Jack Kessler
- 申请人: Yongjun Duan , John Hickey , Rick Panicucci , Jack Kessler
- 申请人地址: MA Framingham
- 专利权人: Symbollon Corporation
- 当前专利权人: Symbollon Corporation
- 当前专利权人地址: MA Framingham
- 主分类号: A61K47/00
- IPC分类号: A61K47/00 ; A61K9/16 ; A61K9/20 ; A61K33/18 ; A61K33/40 ; A61K45/06 ; A61P1/04 ; A61P5/00 ; A61P15/00 ; A61P15/14 ; A61P35/00 ; A61P43/00 ; A61K9/00
摘要:
The invention is a method of administering therapeutic iodine for treating a disorder in a mammal. The invention comprises a step of feeding said mammal an effective amount of an oxidant for an iodine species and an iodine reductant which will cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of the mammal. This is done such that molecular iodine is generated in vivo at a ratio of molecular iodine to total iodine of above at least about 0.65. The invention also discloses a non-aqueous pharmaceutically acceptable carrier with said oxidant and reductant having the ability to cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of said mammal and in an amount sufficient to generate molecular iodine, in vivo, at a ratio of molecular iodine to total iodine of above at least about 0.65.
公开/授权文献
- US5346845A Process for forming a trench capacitor memory cell 公开/授权日:1994-09-13
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