发明授权
- 专利标题： Quinolones and their therapeutic use
- 专利标题（中）： 喹诺酮类及其治疗用途
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申请号： US691338申请日： 1996-08-02
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公开(公告)号： US5891878A公开(公告)日： 1999-04-06
- 发明人: Steven Colin Beasley , John Gary Montana , Hazel John Dyke , Alan Findlay Haughan , Karen Ann Runcie , David Thomas Manallack , George Martin Buckley , Robert James Maxey , Hannah Jayne Kendall , Andrew Douglas Baxter
- 申请人： Steven Colin Beasley , John Gary Montana , Hazel John Dyke , Alan Findlay Haughan , Karen Ann Runcie , David Thomas Manallack , George Martin Buckley , Robert James Maxey , Hannah Jayne Kendall , Andrew Douglas Baxter
- 申请人地址： GBX
- 专利权人： Chiroscience Limited
- 当前专利权人： Chiroscience Limited
- 当前专利权人地址： GBX
- 优先权： GBX9515811 19950802; GBX9526377 19951222; GBX9605868 19960320; GBX9611898 19960607
- 主分类号： C07D215/54
- IPC分类号： C07D215/54 ; A61K31/00 ; A61K31/435 ; A61K31/439 ; A61K31/444 ; A61K31/47 ; A61K31/4709 ; A61P1/00 ; A61P1/04 ; A61P3/00 ; A61P3/10 ; A61P7/00 ; A61P7/12 ; A61P9/00 ; A61P11/00 ; A61P11/06 ; A61P17/00 ; A61P19/00 ; A61P19/02 ; A61P19/08 ; A61P25/16 ; A61P25/28 ; A61P27/00 ; A61P27/02 ; A61P27/16 ; A61P29/00 ; A61P31/00 ; A61P31/12 ; A61P35/00 ; A61P37/00 ; A61P37/08 ; A61P43/00 ; C07D215/56 ; C07D401/06 ; C07D401/14 ; C07D471/04 ; C07D491/048 ; A61K31/50 ; A61K31/505
摘要：
1-Alkyl-substituted-quinolone-3-carboxamides have therapeutic utility via inhibition of Phosphodiesterase IV esterase and/or Tumour Necrosis Factor activity. The compounds of the invention have the general formula (I): ##STR1## The compounds of the invention encompassed by formula (I) include enantiomers, diastereoisomers and mixtures, including racemic mixtures.
公开/授权文献
- US5168128A Anti-tangle spaced stiffeners for elongated flexible members 公开/授权日：1992-12-01
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