- 专利标题： Chemical modification of proteins to improve biocompatibility and bioactivity
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申请号： US911224申请日： 1997-08-15
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公开(公告)号： US5900404A公开(公告)日： 1999-05-04
- 发明人: Colin Gegg , Olaf Kinstler
- 申请人： Colin Gegg , Olaf Kinstler
- 申请人地址： CA Thousand Oaks
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 当前专利权人地址： CA Thousand Oaks
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K47/48 ; C07K1/107 ; C07K14/53 ; C07K14/535 ; C07K14/575
摘要：
The present invention broadly relates to chemical modification of biologically active proteins or analogs thereof. More specifically, the present invention describes novel methods for site-specific chemical modification of various proteins, and resultant compositions having improved biocompatibility and bioactivity.
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