发明授权
- 专利标题: Non-antigenic amine derived polymers and polymer conjugates
- 专利标题(中): 非抗原胺衍生的聚合物和聚合物共轭物
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申请号: US974532申请日: 1997-11-19
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公开(公告)号: US5902588A公开(公告)日: 1999-05-11
- 发明人: Richard B. Greenwald , Anthony Martinez , Annapurna Pendri
- 申请人: Richard B. Greenwald , Anthony Martinez , Annapurna Pendri
- 申请人地址: NJ Piscataway
- 专利权人: Enzon, Inc.
- 当前专利权人: Enzon, Inc.
- 当前专利权人地址: NJ Piscataway
- 主分类号: A61K31/335
- IPC分类号: A61K31/335 ; A61K31/495 ; A61K38/00 ; A61K38/43 ; A61K39/44 ; A61K47/48 ; C07K14/805 ; C07K16/00 ; C07K17/14 ; C08F8/30 ; C08F20/54 ; C08F26/10 ; C08G65/32 ; C08G65/329 ; C08G65/333 ; A61K45/00 ; C08F110/02
摘要:
Substantially non-antigenic polymers containing pI and/or pH optimum modulating moieties are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed.
公开/授权文献
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