发明授权
US5906987A Treatment of male climacteric disorders with nitric oxide synthase
substrates and/or donors, in combination with androgens and/or
aromatase inhibitors
失效
与雄激素和/或芳香酶抑制剂联合治疗一氧化氮合酶底物和/或供体的男性更年期障碍
- 专利标题： Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in combination with androgens and/or aromatase inhibitors
- 专利标题（中）： 与雄激素和/或芳香酶抑制剂联合治疗一氧化氮合酶底物和/或供体的男性更年期障碍
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申请号： US812912申请日： 1997-03-10
-
公开(公告)号： US5906987A公开(公告)日： 1999-05-25
- 发明人: Kristof Chwalisz , Robert E. Garfield
- 申请人： Kristof Chwalisz , Robert E. Garfield
- 申请人地址： DEX Berlin TX Austin
- 专利权人： Schering Aktiengesellschaft and Board of Regents,The University of Texas System
- 当前专利权人： Schering Aktiengesellschaft and Board of Regents,The University of Texas System
- 当前专利权人地址： DEX Berlin TX Austin
- 主分类号： A61K31/565
- IPC分类号： A61K31/565 ; A61K33/26 ; A61K31/56 ; A61K31/13 ; A61K31/195 ; A61K31/34 ; A61K31/535
摘要：
The symptoms of climacterium in male mammals, e.g., hypertension, cardiovascular disease and osteoporosis, are ameliorated by the administration to an afflicted individual one or both of a nitric oxide substrate and/or nitric acid donor, in combination with an androgen, an aromatase inhibitor or both, wherein the circulating levels of testosterone in the afflicted individual are increased.
公开/授权文献
- US4633964A Snowmobile 公开/授权日：1987-01-06
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