发明授权
- 专利标题: Alkylated styrenes as prodrugs to COX-2 inhibitors
- 专利标题(中): 烷基化苯乙烯作为前药转化为COX-2抑制剂
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申请号: US128140申请日: 1998-08-03
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公开(公告)号: US5925631A公开(公告)日: 1999-07-20
- 发明人: Cameron Black , Greg Hughes , Erich Grimm , Serge Leger , Petpiboon Prasit , Zhaoyin Wang
- 申请人: Cameron Black , Greg Hughes , Erich Grimm , Serge Leger , Petpiboon Prasit , Zhaoyin Wang
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C311/29
- IPC分类号: C07C311/29 ; C07C317/22 ; C07C317/24 ; C07C317/44 ; C07C317/46 ; C07D307/58 ; C07D307/60 ; C07D307/64 ; C07D307/66 ; C07D307/94 ; C07D405/12 ; C07D209/44 ; A61K31/44 ; A61K31/445 ; A61K31/47 ; C07D211/22 ; C07D213/30 ; C07D217/16 ; C07D307/32
摘要:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
公开/授权文献
- US4279487A Adapter for coupling a camera to an optical instrument 公开/授权日:1981-07-21