A barometric and altitude bomb detector and midair explosion avoidance system has reinforced armored chamber for containing air travel passenger luggage which is capable of regulating the atmospheric pressure within the chamber. The present invention is designed to track and safely activate bombs that operate according to barometric and altimeter triggering systems by regulating the atmospheric pressure inside the chamber to a similar atmospheric pressure which exists at high altitude (or to air pressure which exist in intercontinental air travel or during climb up), such that the bomb's barometric or altimeter triggering device, which are sensitive to high altitude atmospheric pressures, will move a diaphragm which pushes a switch connected to a battery and which by electric charge blasts the cap and detonates the bomb. The chamber, is capable on the same principal, to detect an altimeter bomb hidden in luggage, by applying low and appropriate atmospheric pressure to the luggage such that the bomb's triggering system will be activated and the bomb will explode safely ont he ground (i.e., before boarding the airplane cargo hold or the passenger cabin). In addition, the chamber includes a camera which will video tape the test inside the chamber, pinpointing and identifying the exact location of the bomb and the luggage that carried the bomb. To ensure that a bomb which is connected to a timer and a barometric triggering device will not escape detection on the ground and be set off in flight, the cargo will be placed inside a pressurized cargo hold an atmospheric pressure maintained at a similar or higher level than ground pressure. Thus, the diaphragm of the bomb triggering device will be prevented from moving and blasting the bomb-cap. This method of handling cargo has an important role in countering terrorism if a bomb has bypassed the atmospheric test on the ground.