发明授权
US5935936A Compositions comprising cationic amphiphiles and co-lipids for
intracellular delivery of therapeutic molecules
失效
包含阳离子两亲物和用于细胞内递送治疗性分子的共 - 脂质的组合物
- 专利标题: Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules
- 专利标题(中): 包含阳离子两亲物和用于细胞内递送治疗性分子的共 - 脂质的组合物
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申请号: US657238申请日: 1996-06-03
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公开(公告)号: US5935936A公开(公告)日: 1999-08-10
- 发明人: Allen J. Fasbender , Michael J. Welsh , Craig S. Siegel , Edward R. Lee , Chau-Dung Chang , John Marshall , Seng H. Cheng , David J. Harris , Simon J. Eastman , Shirley C. Hubbard , Mathieu B. Lane , Eric A. Rowe , Ronald K. Scheule , Nelson S. Yew
- 申请人: Allen J. Fasbender , Michael J. Welsh , Craig S. Siegel , Edward R. Lee , Chau-Dung Chang , John Marshall , Seng H. Cheng , David J. Harris , Simon J. Eastman , Shirley C. Hubbard , Mathieu B. Lane , Eric A. Rowe , Ronald K. Scheule , Nelson S. Yew
- 申请人地址: MA Cambridge IA Iowa City
- 专利权人: Genzyme Corporation,University of Iowa
- 当前专利权人: Genzyme Corporation,University of Iowa
- 当前专利权人地址: MA Cambridge IA Iowa City
- 主分类号: A61K47/28
- IPC分类号: A61K47/28 ; A61K9/127 ; A61K31/70 ; A61K31/7088 ; A61K48/00 ; C07K14/47 ; C12N15/88 ; A01N43/04
摘要:
Novel compositions are provided. Typically, the compositions comprise one or more neutral co-lipids and also a cationic amphiphile. Therapeutic compositions are prepared according to the practice of the invention by contacting a therapeutically active molecule with a dispersion of neutral co-lipid(s) and amphiphile(s).
公开/授权文献
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