发明授权
US5942254A Phosphorylated recombinant human .beta.-casein expressed in a bacterial
system
失效
在细菌系统中表达的磷酸化重组人β-酪蛋白
- 专利标题： Phosphorylated recombinant human .beta.-casein expressed in a bacterial system
- 专利标题（中）： 在细菌系统中表达的磷酸化重组人β-酪蛋白
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申请号： US554137申请日： 1995-11-06
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公开(公告)号： US5942254A公开(公告)日： 1999-08-24
- 发明人: Pradip Mukerji , Jennifer Marie Thurmond , Lennart Hansson , Jeffrey Harris Baxter , Robert George Hards
- 申请人： Pradip Mukerji , Jennifer Marie Thurmond , Lennart Hansson , Jeffrey Harris Baxter , Robert George Hards
- 申请人地址： IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL Abbott Park
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C12N9/12 ; C12N15/62 ; C12N15/64 ; C12N15/67 ; C12N15/70 ; A61K35/20 ; A23C9/15 ; A23J1/20 ; A61K38/17
摘要：
The present invention provides a plasmid containing a promoter sequence, a nucleotide sequence encoding an exogenous protein, and a nucleotide sequence encoding an enzyme capable of modifying the exogenous protein. In a specific embodiment of the invention the encoded exogenous protein is human .beta.-casein and the encoded enzyme is a human kinase capable of phosphorylating recombinant .beta.-casein in a bacterial system. Phosphorylated recombinant human .beta.-casein synthesized using the plasmid of the invention is shown to have the same bioactivity as native human .beta.-casein.
公开/授权文献
- US5162170A Electrode for secondary battery 公开/授权日：1992-11-10
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