发明授权
- 专利标题: Transition state analogs
- 专利标题(中): 过渡状态类比
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申请号: US333237申请日: 1994-11-02
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公开(公告)号: US5952462A公开(公告)日: 1999-09-14
- 发明人: Michael J. Powell , Richard C. Titmas , Richard J. Massey
- 申请人: Michael J. Powell , Richard C. Titmas , Richard J. Massey
- 申请人地址: MD Gaithersburg
- 专利权人: IGEN International Inc.
- 当前专利权人: IGEN International Inc.
- 当前专利权人地址: MD Gaithersburg
- 主分类号: C07C237/22
- IPC分类号: C07C237/22 ; C07K16/10 ; C12N9/00 ; C12Q1/25 ; C07K5/12 ; A61K38/12
摘要:
Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Haptens include, among others, silicon and boron containing compounds. Antibodies which are catalytically active for chemical reactions, in particular, the cleavage or formation of a selected peptide linkage or an ester bond, and which are elicited by such antigens are disclosed as well as methods for producing the antibodies and methods for catalyzing the cleavage or formation of a peptide linkage or in ester bond in a molecule.
公开/授权文献
- US4913399A Solenoid valve assembly 公开/授权日:1990-04-03