A mobile computer work station for a personal computer is disclosed comprising a wheel mounted cabinet (12) for enclosing the computer CPU therein and supporting a computer monitor thereon. A concave vertical partition (18) mounts to a forward side of the cabinet (12) and defines a three sided user station providing improved acoustic and visual isolation to the user. A window (120) extends through the partition (18) and receives the screen of the computer monitor therein. A bezel plate (26) affixes to a forward side of the partition (18) and surrounds the window (120). A lower portion (122) of the plate (26) protects the controls to the monitor there behind from unauthorized tampering. A speaker cavity is defined behind the lower plate portion (122) likewise isolated thereby from unauthorized contact. S-shaped support bars (14, 16) structurally connect cabinet (12) and partition (18) and support a keyboard support plate (20) upon bar segments (98) within the concave partition (18). A second bezel plate (24) attaches to a top surface of plate (20) to retain a touch sensitive keyboard component thereon.