发明授权
US5962319A Human-Th1-specific protein, gene encoding the protein, transformants,
recombinant vectors, and antibodies related to the gene
失效
人Th1特异性蛋白质,编码蛋白质的基因,转化体,重组载体和与该基因相关的抗体
- 专利标题: Human-Th1-specific protein, gene encoding the protein, transformants, recombinant vectors, and antibodies related to the gene
- 专利标题(中): 人Th1特异性蛋白质,编码蛋白质的基因,转化体,重组载体和与该基因相关的抗体
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申请号: US869793申请日: 1997-06-05
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公开(公告)号: US5962319A公开(公告)日: 1999-10-05
- 发明人: Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Shoichi Takano
- 申请人: Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Shoichi Takano
- 申请人地址: JPX Saitama
- 专利权人: BML, Inc.
- 当前专利权人: BML, Inc.
- 当前专利权人地址: JPX Saitama
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; C12N15/12 ; C12N5/10
摘要:
An element for specifying the condition and type of immune-related diseases on the basis of the knowledge about the polarization of distribution of Th1/Th2 subsets of helper T cells. The element for specifying or correcting the polarization of the Th1/Th2 subsets is implemented by use of a recombinant vector, a transformant, a human-Th1-specific protein, and an antibody which uses the human-Th1-specific protein as an antigen. A human-Th1-specific gene is prepared and specified by a subtraction technique and is incorporated into the recombinant vector. The transformant is formed by transforming the recombinant vector. The Th1-specific protein is encoded by the gene derived from the transformant.
公开/授权文献
- US5273773A Protein partial degradation products 公开/授权日:1993-12-28
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