发明授权
US5962525A 6,7-disubstituted-2-aminotetralines active as immunomodulators and
pharmaceutical compositions containing same
失效
作为免疫调节剂起作用的6,7-二取代-2-氨基三
线酯和含有它们的药物组合物
线酯和含有它们的药物组合物
- 专利标题: 6,7-disubstituted-2-aminotetralines active as immunomodulators and pharmaceutical compositions containing same
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专利标题(中):
作为免疫调节剂起作用的6,7-二取代-2-氨基三
线酯和含有它们的药物组合物 -
申请号: US871050申请日: 1997-06-09
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公开(公告)号: US5962525A公开(公告)日: 1999-10-05
- 发明人: Piero Foresta , Mauro Marzi , Maria Ornella Tinti
- 申请人: Piero Foresta , Mauro Marzi , Maria Ornella Tinti
- 申请人地址: ITX Ciampino
- 专利权人: Sigma-Tau
- 当前专利权人: Sigma-Tau
- 当前专利权人地址: ITX Ciampino
- 优先权: ITX48066/90 19900615
- 主分类号: A61K31/135
- IPC分类号: A61K31/135 ; A61K31/216 ; A61K31/675 ; A61P37/00 ; C07C211/38 ; C07C217/74 ; C07C219/26 ; A61K31/225
摘要:
6,7-disubstituted-2-aminotetralines of general formula (1) ##STR1## and their pharmacologically acceptable salts, wherein X and Y, identical or different are selected from the group consisting of methoxy, acetoxy and fluoro; and R and R.sub.1, identical or different, are selected from the group consisting of hydrogen, ethyl, propyl, cyclopropylmethyl, 2-hydroxy-2-phenylethyl, 2-hydroxy-2-(4-methylphenyl)ethyl and 2-hydroxy-3-(4-methoxyphenoxy)propyl are endowed with immunomodulator activity.
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