发明授权
US5965434A Amphipathic PH sensitive compounds and delivery systems for delivering
biologically active compounds
失效
两亲PH敏感化合物和用于递送生物活性化合物的递送系统
- 专利标题： Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
- 专利标题（中）： 两亲PH敏感化合物和用于递送生物活性化合物的递送系统
-
申请号： US365841申请日： 1994-12-29
-
公开(公告)号： US5965434A公开(公告)日： 1999-10-12
- 发明人: Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
- 申请人： Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
- 专利权人： Wolff; Jon A.,Budker; Vladimir,Gurevich; Vladimir
- 当前专利权人： Wolff; Jon A.,Budker; Vladimir,Gurevich; Vladimir
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; C07C219/06 ; C07C239/12 ; C07C279/12 ; C07D295/092 ; C07D295/13 ; C12N15/88 ; C12N15/63
摘要：
The present invention provides amphipathic lipid compounds comprising a hydrophilic, catonic, pH-sensitive moiety, the positive charge of which moiety increases as pH decreases over the pH range of 8.0 to 4.5. Vesicular delivery systems comprising such amphipathic compounds and the use of those systems for delivering biologically active substances to cells are also provided.
公开/授权文献
- USD276761S Field case for a camera 公开/授权日：1984-12-18
信息查询
