发明授权
US5968963A PLA.sub.2 inhibitors and their use for inhibition of intestinal
cholesterol absorption
失效
PLA2抑制剂及其用于抑制胆固醇吸收的用途
- 专利标题: PLA.sub.2 inhibitors and their use for inhibition of intestinal cholesterol absorption
- 专利标题(中): PLA2抑制剂及其用于抑制胆固醇吸收的用途
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申请号: US610030申请日: 1996-03-04
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公开(公告)号: US5968963A公开(公告)日: 1999-10-19
- 发明人: Reynold Homan
- 申请人: Reynold Homan
- 申请人地址: NJ Morris Plains
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: NJ Morris Plains
- 主分类号: A61K31/047
- IPC分类号: A61K31/047 ; A61K31/05 ; A61K31/16 ; A61K31/195 ; A61K31/196 ; A61K31/215 ; A61K31/40 ; A61K31/41 ; A61K31/66 ; A61K45/00 ; A61P3/06 ; A61P9/10 ; A61P43/00 ; C07C15/16 ; C07C22/08 ; C07C25/18 ; C07C229/40 ; C07C229/44 ; C07C233/09 ; C07C255/28 ; C07C323/36 ; C07C323/63 ; C07D207/08 ; C07D257/04 ; C07F9/40 ; C07D257/06
摘要:
Certain compounds have been synthesized and found to be effective inhibitors of phospholipase A.sub.2 (PLA.sub.2), and thereby useful in the treatment of intestinal cholesterol absorption and the disease states arising therefrom, such as hypercholesterolemia and coronary artery disease.
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