发明授权
US5972961A 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators
失效
4-芳基-3-氨基喹啉-2-酮衍生物作为钾通道调节剂
- 专利标题： 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators
- 专利标题（中）： 4-芳基-3-氨基喹啉-2-酮衍生物作为钾通道调节剂
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申请号： US138638申请日： 1998-08-24
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公开(公告)号： US5972961A公开(公告)日： 1999-10-26
- 发明人: Piyasena Hewawasam , John E. Starrett, Jr. , Stephen G. Swartz
- 申请人： Piyasena Hewawasam , John E. Starrett, Jr. , Stephen G. Swartz
- 申请人地址： NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： NJ Princeton
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61P1/00 ; A61P9/10 ; A61P11/06 ; A61P25/00 ; A61P43/00 ; C07D215/38 ; C07D405/12 ; C07D215/16 ; A01N43/42
摘要：
The present invention provides novel 4-aryl-3-aminoquinolin-2-one derivatives having the general formula ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as defined herein, or a non-toxic pharmaceutically acceptable salt thereof which are modulators of the large conductance calcium-activated K.sup.+ channels and are useful in the treatment of disorders which are responsive to the opening of the potassium channels.
公开/授权文献
- US5533798A Lock system for casegoods 公开/授权日：1996-07-09
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