发明授权
- 专利标题： Process for preparing 3-norcephem compounds
- 专利标题（中）： 3-诺司匹林化合物的制备方法
-
申请号： US11041申请日： 1998-02-06
-
公开(公告)号： US5977352A公开(公告)日： 1999-11-02
- 发明人: Michio Sasaoka , Sigeru Torii , Hideo Tanaka , Ryo Kikuchi , Yutaka Kameyama
- 申请人： Michio Sasaoka , Sigeru Torii , Hideo Tanaka , Ryo Kikuchi , Yutaka Kameyama
- 申请人地址： JPX Osaka
- 专利权人： Otsuka Kagaku Kabushiki Kaisha
- 当前专利权人： Otsuka Kagaku Kabushiki Kaisha
- 当前专利权人地址： JPX Osaka
- 优先权： JPX8-175529 19960613
- 主分类号： C07D501/00
- IPC分类号： C07D501/00 ; C07D501/08 ; C07D501/16 ; C07D501/20 ; C07D501/22
摘要：
The present invention provides a process for preparing 3-norcephem compound represented by the formula (2), characterized in that a hydride reagent is acted on a halogenated .beta.-lactam compound represented by the formula (1) in the presence of a cuprous compound ##STR1## wherein R.sub.1 is a hydrogen atom, amino group or protected amino group, R.sub.2 is an aryl or substituted aryl, n is 0 to 2, R.sub.3 is a hydrogen atom or carboxylic acid protective group, X is a halogen atom, and Y is a halogen atom or a leaving group ##STR2## wherein R.sub.1 and R.sub.3 are as defined above.
公开/授权文献
- US4738425A Computer printer support 公开/授权日：1988-04-19
信息查询
