发明授权
US5989551A Materials and methods for detection and treatment of insulin-dependent
diabetes
失效
用于胰岛素依赖性糖尿病检测和治疗的材料和方法
- 专利标题: Materials and methods for detection and treatment of insulin-dependent diabetes
- 专利标题(中): 用于胰岛素依赖性糖尿病检测和治疗的材料和方法
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申请号: US548159申请日: 1995-10-25
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公开(公告)号: US5989551A公开(公告)日: 1999-11-23
- 发明人: Noel K. Maclaren , Abner L. Notkins , Michael S. Lan , Qing Li
- 申请人: Noel K. Maclaren , Abner L. Notkins , Michael S. Lan , Qing Li
- 申请人地址: DC Washington FL Gainesville
- 专利权人: The United States of America as represented by the Department of Health and Human Services,The University of Florida
- 当前专利权人: The United States of America as represented by the Department of Health and Human Services,The University of Florida
- 当前专利权人地址: DC Washington FL Gainesville
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K39/00 ; A61P3/10 ; A61P37/02 ; C07K14/47 ; C07K14/705 ; C12N9/16
摘要:
The method and compositions of this invention provide an effective and reliable substitute for the currently employed ICA assay for diabetes. By providing a method for detecting autoantibodies to GAD.sub.65, IA-2 and a previously unidentified antigen termed IA-2.beta. herein, the method provides a chemical assay which has improved reliability. In addition, these antigens may be employed in therapeutic regimens aimed at achieving amelioration of the clinical condition.
公开/授权文献
- US3972878A Method for preparing azines and hydrazones 公开/授权日:1976-08-03
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