Invention Grant
US5994379A Bisaryl COX-2 inhibiting compounds, compositions and methods of use
失效
二芳基COX-2抑制化合物，组合物和使用方法
- Patent Title: Bisaryl COX-2 inhibiting compounds, compositions and methods of use
- Patent Title (中): 二芳基COX-2抑制化合物，组合物和使用方法
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Application No.: US246925Application Date: 1999-02-09
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Publication No.: US5994379APublication Date: 1999-11-30
- Inventor: Christopher I. Bayly , Cameron Black , Nathalie Ouimet , David Percival , Serge Leger , Marc Ouellet
- Applicant: Christopher I. Bayly , Cameron Black , Nathalie Ouimet , David Percival , Serge Leger , Marc Ouellet
- Applicant Address: CAX Kirkland
- Assignee: Merck Frosst Canada, Inc.
- Current Assignee: Merck Frosst Canada, Inc.
- Current Assignee Address: CAX Kirkland
- Main IPC: C07D333/60
- IPC: C07D333/60 ; A61K31/192 ; A61K31/216 ; A61K31/34 ; A61K31/343 ; A61K31/381 ; A61K31/403 ; A61K31/4035 ; A61K31/404 ; A61K31/41 ; A61K31/4184 ; A61K31/423 ; A61K31/428 ; A61K31/437 ; A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4418 ; A61K31/495 ; A61K31/496 ; A61K31/4985 ; A61P1/00 ; A61P3/10 ; A61P11/06 ; A61P15/06 ; A61P19/02 ; A61P19/06 ; A61P19/10 ; A61P25/04 ; A61P25/06 ; A61P25/28 ; A61P27/02 ; A61P27/06 ; A61P29/00 ; A61P31/12 ; A61P35/00 ; A61P35/04 ; A61P37/02 ; A61P43/00 ; C07C57/42 ; C07C59/64 ; C07C69/618 ; C07C69/734 ; C07C323/62 ; C07D209/08 ; C07D209/18 ; C07D209/44 ; C07D213/55 ; C07D213/64 ; C07D213/69 ; C07D235/08 ; C07D263/56 ; C07D277/64 ; C07D307/79 ; C07D333/54 ; C07D471/04 ; A61K31/425 ; A61K31/19 ; A61K31/215 ; A61K31/38 ; A61K31/42 ; C07C57/38 ; C07C321/28 ; C07D235/06
Abstract:
The present invention relates to inhibitors of COX-2, compositions which contain such compounds and methods of use. The compounds are represented by formula I: ##STR1## and include pharmaceutically acceptable salts and esters thereof.
Public/Granted literature
- US5425684A Variable speed power transmission mechanism Public/Granted day:1995-06-20
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