发明授权
- 专利标题： Arylsulfonamides as phospholipase A.sub.2 inhibitors
- 专利标题（中）： 芳基磺酰胺作为磷脂酶A2抑制剂
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申请号： US766554申请日： 1996-12-11
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公开(公告)号： US5994398A公开(公告)日： 1999-11-30
- 发明人: Varghese John , Russell E. Rydel , Eugene D. Thorsett
- 申请人： Varghese John , Russell E. Rydel , Eugene D. Thorsett
- 申请人地址： CA South San Francisco
- 专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人地址： CA South San Francisco
- 主分类号： C07C311/46
- IPC分类号： C07C311/46 ; C07D257/04 ; C07D307/54 ; C07D333/28 ; A01N47/10 ; A01N47/28 ; C07C273/00 ; C07C333/00
摘要：
Arylsulfonamides which have the general structure: with the symbols R.sup.1, R.sup.2, R.sup.3, R.sup.4, A and n representing the groups and integers provided in the detailed description are provided herein. These compounds have activity as inhibitors of phospholipase A2, inhibitors of cytokine release and as inhibitors of neurodegeneration.
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