发明授权
US6011063A Ortho-substituted benzoylguanidines, process for their preparation,
their use as a medicament or diagnostic, and medicament comprising them
失效
正离子取代的苯甲酰胍，其制备方法，它们作为药物或诊断剂的用途，以及包含它们的药物
- 专利标题： Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them
- 专利标题（中）： 正离子取代的苯甲酰胍，其制备方法，它们作为药物或诊断剂的用途，以及包含它们的药物
-
申请号： US868077申请日： 1997-06-03
-
公开(公告)号： US6011063A公开(公告)日： 2000-01-04
- 发明人: Andreas Weichert , Joachim Brendel , Heinz-Werner Kleemann , Hans Jochen Lang , Jan-Robert Schwark , Udo Albus , Wolfgang Scholz
- 申请人： Andreas Weichert , Joachim Brendel , Heinz-Werner Kleemann , Hans Jochen Lang , Jan-Robert Schwark , Udo Albus , Wolfgang Scholz
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX19622370 19960604
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A01N1/02 ; A01N47/44 ; A61K31/155 ; A61P3/00 ; A61P3/06 ; A61P7/04 ; A61P9/00 ; A61P9/06 ; A61P9/08 ; A61P9/10 ; A61P35/00 ; C07C279/22 ; C07C319/20 ; C07C323/62 ; A61K31/275 ; A61K31/22 ; A61K31/24
摘要：
Ortho-substituted benzoylguanidines of the formula I ##STR1## in which R(1) to R(5) have the meanings given in the claims, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and for infarct treatment and also for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiological processes in the formation of ischemically induced damage, in particular in the illicitation of ischemically induced cardiac arrhythmias.
公开/授权文献
- US5238886A Surface bonding of ceramic bodies 公开/授权日：1993-08-24
信息查询
