The instant invention relates to a method and an arrangement for the space-based operation of quantum-optical amplifiers embodied as optical waveguides, while taking the special conditions to be found in space into consideration. An amplifier housing 2 filled with nitrogen has a cutout into which a plan-parallel quartz glass plate 4 has been fitted, through which light beams can enter and leave the housing. The amplifier housing 2 rests on heat-insulating supports 3a, 3b and is temperature-stabilized by a Peltier element 5. The amplifier housing 2 is filled with nitrogen in order to achieve operating conditions similar to those on earth.