发明授权
- 专利标题： Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
- 专利标题（中）： 用锌盐预处理的人生长激素的药物制剂
-
申请号： US121386申请日： 1998-07-23
-
公开(公告)号： US06022858A公开(公告)日： 2000-02-08
- 发明人: Hans Holmegaard S.o slashed.rensen , Ole Hvilsted Olsen , Lars Thim , Christensen Thorkild , Per Balschmidt
- 申请人： Hans Holmegaard S.o slashed.rensen , Ole Hvilsted Olsen , Lars Thim , Christensen Thorkild , Per Balschmidt
- 申请人地址： DKX Bagsvaerd
- 专利权人： Novo Nordisk A/S
- 当前专利权人： Novo Nordisk A/S
- 当前专利权人地址： DKX Bagsvaerd
- 优先权： DKX2046/91 19911220; DKX1364/92 19921110; WOXPCT/DK92/00379 19921216
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/27 ; C07K14/61
摘要：
A pharmaceutical formulation comprising a growth hormone pretreated with zinc and optionally lysine or calcium ions shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
公开/授权文献
- US4331309A Programmed aircraft arresting system 公开/授权日：1982-05-25
信息查询
IPC分类:
