发明授权
US6030942A Peptides peptide analogs peptidomimetics and other small molecules
useful for inhibiting the activity of ribonucleotide reductase
失效
肽肽类似物肽模拟物和其他可用于抑制核糖核苷酸还原酶活性的小分子
- 专利标题: Peptides peptide analogs peptidomimetics and other small molecules useful for inhibiting the activity of ribonucleotide reductase
- 专利标题(中): 肽肽类似物肽模拟物和其他可用于抑制核糖核苷酸还原酶活性的小分子
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申请号: US40216申请日: 1998-03-17
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公开(公告)号: US6030942A公开(公告)日: 2000-02-29
- 发明人: Barry S. Cooperman , Ralph F. Hirschmann , Amos B. Smith, III , Paul Laub , Setsuya Sasho , Paul A. Sprengeler , Bari A. Barwis , Alison Fisher , Shrikumar Nair
- 申请人: Barry S. Cooperman , Ralph F. Hirschmann , Amos B. Smith, III , Paul Laub , Setsuya Sasho , Paul A. Sprengeler , Bari A. Barwis , Alison Fisher , Shrikumar Nair
- 申请人地址: PA Philadelphia
- 专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人地址: PA Philadelphia
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C12N9/02 ; A61K38/12 ; A61K38/16
摘要:
The invention relates to compositions which are useful for inhibiting ribonucleotide reductase enzymes, including the mammalian ribonucleotide reductase enzyme. The compositions include, but are not limited to, linear peptides, cyclic peptides, peptide analogs, and peptidomimetics. Methods of using the compositions of the invention to treat cancer and viral and bacterial infections are disclosed.
公开/授权文献
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