发明授权
US6034110A Method for preventing onset of restenosis after angioplasty employing an
RXR-specific retinoid and a PPAR.gamma. ligand
失效
使用RXR特异性类视黄醇和PPARγ配体预防血管成形术后再狭窄发作的方法
- 专利标题: Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid and a PPAR.gamma. ligand
- 专利标题(中): 使用RXR特异性类视黄醇和PPARγ配体预防血管成形术后再狭窄发作的方法
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申请号: US5790申请日: 1998-01-12
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公开(公告)号: US6034110A公开(公告)日: 2000-03-07
- 发明人: Sunil Nagpal , Roshantha A. Chandraratna
- 申请人: Sunil Nagpal , Roshantha A. Chandraratna
- 申请人地址: CA Irvine
- 专利权人: Allergan Sales, Inc.
- 当前专利权人: Allergan Sales, Inc.
- 当前专利权人地址: CA Irvine
- 主分类号: A61K45/06
- IPC分类号: A61K45/06 ; A61K31/44 ; A61K31/19 ; A61K31/38 ; A61K31/415 ; A61K31/425
摘要:
A method is provided for preventing or reducing the risk of restenosis following angioplasty by administering a retinoid, such as an RXR-selective retinoid, e.g. the compound of the formula: ##STR1## and a PPAR.gamma. specific ligand and pharmaceutically acceptable salts and esters and amides thereof.
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