发明授权
- 专利标题： Filamentous hemagglutinin of B. pertussis
- 专利标题（中）： 百日咳杆菌的丝状血凝素
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申请号： US299941申请日： 1994-09-01
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公开(公告)号： US6036960A公开(公告)日： 2000-03-14
- 发明人: David A. Relman , Mario Domenighini , Rino Rappuoli , Stanley Falkow
- 申请人： David A. Relman , Mario Domenighini , Rino Rappuoli , Stanley Falkow
- 专利权人： Relman; David A.,Domenighini; Mario,Rappuoli; Rino,Falkow; Stanley
- 当前专利权人： Relman; David A.,Domenighini; Mario,Rappuoli; Rino,Falkow; Stanley
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P31/04 ; C07K14/235 ; A61K39/10 ; C12P19/34 ; C12P21/06 ; G01N33/53
摘要：
Nucleic acid and protein compositions are provided from B. pertussis which may find use in diagnosis, prevention and therapy of whooping cough. Particularly, an open reading frame encoding filamentous hemagglutinin precursors provided, with the intact protein for the filamentous hemagglutinin portion thereof, can be expressed in a wide variety of hosts, for use in the production of antibodies, for immunodiagnosis or therapy, or as vaccines for prophylactic purposes.
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