发明授权
- 专利标题： Human Th2 specific protein
- 专利标题（中）： 人Th2特异性蛋白
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申请号： US981825申请日： 1998-05-11
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公开(公告)号： US6040426A公开(公告)日： 2000-03-21
- 发明人: Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Syoichi Takano
- 申请人： Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Syoichi Takano
- 申请人地址： JPX Tokyo
- 专利权人： BML, Inc.
- 当前专利权人： BML, Inc.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX8-166793 19960605
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/47 ; C07K14/705 ; C07K16/28 ; C12N15/12 ; C12P21/08 ; C07K14/435
摘要：
The present invention provides for specifying the condition and type of immune-related diseases on the basis of the knowledge about the polarization of the distribution of helper T-cell subsets Th1 and Th2. More sepcifically, in this invention, the gene (B19) specific only the human Th2 is prepared and specified by a subtraction method, and a recombinant vector into which the gene is incorporated, a transformant transformed by the recombinant vector, a human-Th2-specific protein which the gene encodes and which derives from the transformant, and a monoclonal antibody against the Th2-specific protein are produced and the gene, protein, antibody, etc. are used as the means for specifying or correcting the polarization of the distribution of Th1 and Th2 to solve the above object.
公开/授权文献
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