发明授权
- 专利标题： Process for the production of metal-complex carboxylic acid amides
- 专利标题（中）： 制备金属络合物羧酸酰胺的方法
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申请号： US982381申请日： 1997-12-02
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公开(公告)号： US6045776A公开(公告)日： 2000-04-04
- 发明人: Johannes Platzek , Bernd Raduchel , Heribert Schmitt-Willich , Klaus-Dieter Graske
- 申请人： Johannes Platzek , Bernd Raduchel , Heribert Schmitt-Willich , Klaus-Dieter Graske
- 申请人地址： DEX
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX
- 优先权： DEX19652386 19961204
- 主分类号： A61K49/08
- IPC分类号： A61K49/08 ; C07D257/02 ; C07D499/00 ; A61B5/055
摘要：
The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex carboxylic acid and at least one solubilizing substance in dimethyl sulfoxide (DMSO) is pretreated with a dehydrating reagent, optionally with the addition of a coupling adjuvant, and is then reacted with an amine of general formula IA(NH.sub.2).sub.n (I),in whichA stands for the radical of a natural or synthetic amine, andn stands for numbers 1 to 100.
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