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US6051576A Means to achieve sustained release of synergistic drugs by conjugation 失效
通过共轭实现协同药物持续释放的手段

Means to achieve sustained release of synergistic drugs by conjugation
摘要:
A codrug composition of at least two drug compounds covalently linked to one another via a labile bond to form a single codrug composition, or ionically linked to one another to form a single workings composition, and methods of use of the codrug for the treatment of various medical conditions. The codrug may be administered by itself or in the form of a bioerodible or nonbioerodible substance.
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