发明授权
- 专利标题： Cycloalkano-pyridines
- 专利标题（中）： 环烷基 - 吡啶
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申请号： US889530申请日： 1997-07-08
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公开(公告)号： US6069148A公开(公告)日： 2000-05-30
- 发明人: Gunter Schmidt , Arndt Brandes , Rolf Angerbauer , Michael Logers , Matthias Muller-Gliemann , Carsten Schmeck , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt , Joachim Schuhmacher , Henry Giera , Holger Paulsen , Paul Naab , Michael Conrad , Jurgen Stoltefuss
- 申请人： Gunter Schmidt , Arndt Brandes , Rolf Angerbauer , Michael Logers , Matthias Muller-Gliemann , Carsten Schmeck , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt , Joachim Schuhmacher , Henry Giera , Holger Paulsen , Paul Naab , Michael Conrad , Jurgen Stoltefuss
- 申请人地址： DEX Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DEX Leverkusen
- 优先权： DEX19627419 19960708; DEX19707199 19970224
- 主分类号： C07D215/20
- IPC分类号： C07D215/20 ; A61K31/435 ; A61K31/47 ; A61K31/4709 ; A61K31/473 ; A61P3/06 ; A61P9/00 ; A61P9/10 ; C07C225/18 ; C07D215/22 ; C07D215/36 ; C07D215/40 ; C07D215/54 ; C07D221/04 ; C07D221/16 ; C07D221/20 ; C07D405/06 ; C07D491/056 ; C07D491/08 ; C07D491/10 ; C07D491/107 ; C07F7/18 ; A61K31/438 ; C07D215/00 ; C07D217/00
摘要：
The cycloalkano-pyridines are prepared by reacting corresponding cycloalkano-pyridine-aldehydes with suitable organometallic compounds or Wittig or Grignard reagents or reacting compounds of the cycloalkano-pyridine alcohols type with suitable bromine compounds, and optionally varying the functional groups accordingly. The, cycloalkanopyridines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of hyperlipoproteinaemia and arteriosclerosis.