发明授权
- 专利标题: Phosphinic alkanoic acid derivatives
- 专利标题(中): 膦酸链烷酸衍生物
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申请号: US2147申请日: 1997-12-31
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公开(公告)号: US6071965A公开(公告)日: 2000-06-06
- 发明人: Paul F. Jackson , Weixing Li , Keith M. Maclin , Kevin L. Tays , Takashi Tsukamoto , Barbara S. Slusher
- 申请人: Paul F. Jackson , Weixing Li , Keith M. Maclin , Kevin L. Tays , Takashi Tsukamoto , Barbara S. Slusher
- 申请人地址: MD Baltimore
- 专利权人: Guilford Pharmaceuticals Inc.
- 当前专利权人: Guilford Pharmaceuticals Inc.
- 当前专利权人地址: MD Baltimore
- 主分类号: A61K31/00
- IPC分类号: A61K31/00 ; A61K31/194 ; A61K31/66 ; A61K31/665 ; A61K31/67 ; A61K31/675 ; A61K38/05 ; A61K38/06 ; C07F9/30 ; C07F9/32 ; C07F9/38 ; C07F9/40 ; C07F9/44 ; C07F9/58 ; C07F9/655 ; C07F9/6553 ; C12N9/99 ; C07F9/28
摘要:
The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
公开/授权文献
- US5353311A Radio transmitter 公开/授权日:1994-10-04