发明授权
- 专利标题: Reagents for intracellular delivery of macromolecules
- 专利标题(中): 细胞内分泌大分子的试剂
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申请号: US195866申请日: 1994-02-11
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公开(公告)号: US06075012A公开(公告)日: 2000-06-13
- 发明人: Gulilat Gebeyehu , Joel A. Jessee
- 申请人: Gulilat Gebeyehu , Joel A. Jessee
- 申请人地址: MD Gaithersburg
- 专利权人: Life Technologies, Inc.
- 当前专利权人: Life Technologies, Inc.
- 当前专利权人地址: MD Gaithersburg
- 主分类号: A61K48/00
- IPC分类号: A61K48/00
摘要:
The present invention discloses cationic lipids and lipophilic compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Also disclosed are compositions of cationic lipids and viral components or non-viral fusagenic compounds useful for enhancing transfection.
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