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US6075025A Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases 失效
可用于抑制G蛋白功能和治疗增殖性疾病的三环氨基甲酸酯化合物

Tricyclic carbamate compounds useful for inhibition of G-protein
function and for treatment of proliferative diseases
摘要:
A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of Formula 1.0 ##STR1## Also disclosed are novel compounds of the formulas: ##STR2## Also disclosed are processes for making 3-substituted compounds of the Formulas 1.1, 1.2 and 1.3.Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formulas 1.1, 1.2, and 1.3.
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