Invention Grant
- Patent Title: Boron heterocycle steroid mimics and associated pharmaceutical compositions and methods of use
- Patent Title (中): 硼杂环类固醇模拟物和相关药物组合物和使用方法
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Application No.: US236948Application Date: 1999-01-25
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Publication No.: US6083936APublication Date: 2000-07-04
- Inventor: Michael P. Groziak
- Applicant: Michael P. Groziak
- Applicant Address: CA Menlo Park
- Assignee: SRI International
- Current Assignee: SRI International
- Current Assignee Address: CA Menlo Park
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61K31/69 ; A61K49/00 ; A61P5/30 ; A61P11/00 ; A61P15/00 ; A61P19/10 ; A61P35/00 ; C07F5/02 ; A01N55/58 ; C07C69/96 ; C07F5/04
Abstract:
Boron heterocycle steroid mimics are provided that are useful as pharmaceutical agents, particularly in the treatment of estrogen-dependent disorders such as estrogen-dependent cancers. The compounds are also useful in diagnostic techniques such as magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), in boron neutron capture therapy, and in fluorescence emission-based modalities. Pharmaceutical formulations and methods of using the novel compounds are provided as well.
Public/Granted literature
- US5455550A Dual gap electromagnetic actuator having a bypassing pole gap and a variable pole gap Public/Granted day:1995-10-03
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