发明授权
US6084075A Agonist and antagonist antibodies to the chemokine receptor-2 (CCR2)
失效
趋化因子受体-2（CCR2）的激动剂和拮抗剂抗体
- 专利标题： Agonist and antagonist antibodies to the chemokine receptor-2 (CCR2)
- 专利标题（中）： 趋化因子受体-2（CCR2）的激动剂和拮抗剂抗体
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申请号： US734171申请日： 1997-02-28
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公开(公告)号： US6084075A公开(公告)日： 2000-07-04
- 发明人: Peter Lind , Carlos Martinez Alonso , Jose Mario Mellado Garcia , Jose Miguel Rodriguez Frade
- 申请人： Peter Lind , Carlos Martinez Alonso , Jose Mario Mellado Garcia , Jose Miguel Rodriguez Frade
- 申请人地址： SEX Stockholm ESX Madrid
- 专利权人： Pharmacia & Upjohn AB,Consejo Superior de Investigaciones
- 当前专利权人： Pharmacia & Upjohn AB,Consejo Superior de Investigaciones
- 当前专利权人地址： SEX Stockholm ESX Madrid
- 优先权： SEX9600820 19960301
- 主分类号： C12N15/02
- IPC分类号： C12N15/02 ; A61K31/00 ; A61K38/00 ; A61K39/395 ; A61K49/00 ; A61P9/00 ; A61P9/10 ; A61P11/00 ; A61P17/00 ; A61P17/06 ; A61P19/00 ; A61P19/02 ; A61P25/28 ; A61P29/00 ; A61P35/00 ; A61P37/00 ; A61P37/02 ; C07K16/28 ; C12N5/10 ; C12P21/08 ; G01N33/15 ; G01N33/53 ; G01N33/566 ; G01N33/569 ; G01N33/68 ; C07K16/24
摘要：
The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screening and detection of tissues and classes of cells expressing the MCP-1 receptor, for screening for new drugs and for therapeutic use. The invention also relates to a preparation comprising the claimed antibody and a micro-organism or cell-line capable of producing the claimed antibody.
公开/授权文献
- US4619673A Adsorbent device 公开/授权日：1986-10-28
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