发明授权
- 专利标题： Process for the production of an optically active alcohol and a novel optically active alcohol
- 专利标题（中）： 用于制备光学活性醇和新型光学活性醇的方法
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申请号： US260482申请日： 1999-03-02
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公开(公告)号： US6103517A公开(公告)日： 2000-08-15
- 发明人: Takakiyo Mine , Hiroshi Mineta , Tomoyuki Yui , Masahiro Johno
- 申请人： Takakiyo Mine , Hiroshi Mineta , Tomoyuki Yui , Masahiro Johno
- 申请人地址： JPX Tokyo
- 专利权人： Mitsubishi Gas Chemical Company
- 当前专利权人： Mitsubishi Gas Chemical Company
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX2-240519 19960911; JPX8-284749 19960926
- 主分类号： C12P41/00
- IPC分类号： C12P41/00
摘要：
A process for the production of R-configuration or S-configuration optically active alcohol having the formula (1),CH.sub.3 C*H(OH)(CH.sub.2).sub.m OC.sub.n H.sub.2n+1 (1)wherein m is an integer of 3 to 5, n is an integer of 1 to 3, and C* is an asymmetric carbon,and the formula (2), which comprises carrying out the optical resolution of the racemic alcohol,CH.sub.3 CH(OH)(CH.sub.2).sub.m OC.sub.n H.sub.2n+1 (2)wherein m is an integer of 3 to 5 and n is an integer of 1 to 3,into an R-configuration compound and S-configuration compound by the asymmetric trans-esterification thereof is provided in the presence of vinyl propionate as an esterifying agent and a lipase as a catalyst.
公开/授权文献
- US5518731A Nonaqueous fluorinated drug delivery vehicle suspensions 公开/授权日：1996-05-21
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