- 专利标题： Aminotetralin derivative for the therapy of cardiovascular diseases
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申请号： US328434申请日： 1999-06-09
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公开(公告)号： US6103760A公开(公告)日： 2000-08-15
- 发明人: Paolo Chiesi , Stefano Bongrani , Roberta Razzetti , Maurizio Civelli , Alberto Umile
- 申请人： Paolo Chiesi , Stefano Bongrani , Roberta Razzetti , Maurizio Civelli , Alberto Umile
- 申请人地址： ITX Parma
- 专利权人： Chiesi Farmaceuticals S.p.A.
- 当前专利权人： Chiesi Farmaceuticals S.p.A.
- 当前专利权人地址： ITX Parma
- 主分类号： A61K31/135
- IPC分类号： A61K31/135 ; A61K31/136 ; A61K31/221 ; A61K31/222 ; A61K38/55 ; A61P9/00 ; A61P9/04 ; A61P9/10 ; A61K31/21
摘要：
Left ventricular dysfunction is treated by a process, comprising:administering to a subject suffering from left ventricular remodeling a therapeutically effective amount of 5,6-dihydroxy-2-methylaminotetralin, or 5,6-diisobutyroyl-oxy-2-methyl-aminotetralin, or a pharmaceutically acceptable salt thereof in combination with an angiotensin-converting enzyme inhibitor.
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