发明授权
- 专利标题： Human mutT2
- 专利标题（中）： 人类mutT2
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申请号： US916989申请日： 1997-08-21
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公开(公告)号： US6103871A公开(公告)日： 2000-08-15
- 发明人: Ying-Fei Wei , Ewen F. Kirkness
- 申请人： Ying-Fei Wei , Ewen F. Kirkness
- 申请人地址： MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： MD Rockville
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N9/16 ; C07H21/02 ; C07K1/00 ; C12Q1/68
摘要：
A human hMutT2 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for hydrolyzing and eliminating oxidized guanine nucleotides from the nucleotide pool to ensure correct DNA synthesis. Diagnostic assays are also disclosed which detect the presence of a mutated form of hMutT2 and over-expression of the hMutT2 protein.
公开/授权文献
- USD301715S Radio receiver 公开/授权日：1989-06-20
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