发明授权
US06106856A Transdermal delivery of calcium channel blockers, such as nifedipine
失效
透皮递送钙通道阻断剂，如硝苯地平
- 专利标题： Transdermal delivery of calcium channel blockers, such as nifedipine
- 专利标题（中）： 透皮递送钙通道阻断剂，如硝苯地平
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申请号： US398664申请日： 1995-03-03
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公开(公告)号： US06106856A公开(公告)日： 2000-08-22
- 发明人: Emilio Squillante , Anita Nanda , Thomas E. Needham , Hossein Zia
- 申请人： Emilio Squillante , Anita Nanda , Thomas E. Needham , Hossein Zia
- 申请人地址： RI Providence
- 专利权人： The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
- 当前专利权人： The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
- 当前专利权人地址： RI Providence
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/70 ; A61K31/44 ; A61K47/00 ; A61K47/10 ; A61K47/12 ; A61K47/22 ; B60J7/08 ; A61F13/02
摘要：
A transdermal formulation of dihydropyridine calcium antagonists and specifically nifedipine, nimodipine and nitrendipine. The calcium antagonists are dispersed in a mixed liquid. The mixed liquid comprises varying mole fractions of cis-oleic acid and dimethylisosorbide dispersed in a polypropylene glycol base.
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