发明授权
- 专利标题: Bone replacement compound comprising poly(polypropylene fumarate)
- 专利标题(中): 包含聚(聚丙烯富马酸酯)的骨替代化合物
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申请号: US289361申请日: 1999-04-09
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公开(公告)号: US6124373A公开(公告)日: 2000-09-26
- 发明人: Susan J. Peter , Michael J. Yaszemski , Antonios G. Mikos
- 申请人: Susan J. Peter , Michael J. Yaszemski , Antonios G. Mikos
- 申请人地址: TX Houston
- 专利权人: WM. Marsh Rice University
- 当前专利权人: WM. Marsh Rice University
- 当前专利权人地址: TX Houston
- 主分类号: A61L27/00
- IPC分类号: A61L27/00 ; A61L24/00 ; A61L24/04 ; A61L27/18 ; C08G63/52 ; C08G63/56 ; C08G63/78 ; C08K3/32 ; C08L67/06
摘要:
A method for controlling the gel point of a bone cement containing poly(polypropylene fumarate), a cross-linking monomer, an initiator, an inorganic filler, and a radical initiator. The gel point is controlled by varying the molecular weight of the poly(polypropylene fumarate) while maintaining the weight average molecular weight (M.sub.w) of the poly(polypropylene fumarate) above 2000 and the polydispersity index of the poly(polypropylene fumarate) below 2. In a preferred embodiment, the molecular weight of the poly(polypropylene fumarate) greater than 4000, and more preferably greater than 5000.
公开/授权文献
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