In an apparatus for guiding a medical probe into body cavities, a handle housing is provided consisting of inner, upper and lower modules. The inner module comprises a rinsing liquid supply and suctioning hose assembly, which can be removed and discarded after use. The lower housing part includes probe support and guide structures and the upper housing part includes operating slide members engaging the hoses of the hose assembly for controlling the flow through the hoses. It also includes means extending through the inner module and engaging the probe support in the lower module for axially moving the probe support and the probe retained therein. A two-lumina shaft extends from the apparatus in alignment with the probe and receives the probe, and flow communication structures are provided for interconnecting the two hoses with the lumina in the shaft.