发明授权
- 专利标题: Process for producing amide derivatives and intermediates therefor
- 专利标题(中): 制备酰胺衍生物的方法及其中间体
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申请号: US43668申请日: 1998-04-14
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公开(公告)号: US6133461A公开(公告)日: 2000-10-17
- 发明人: Takashi Inaba , Yasuki Yamada
- 申请人: Takashi Inaba , Yasuki Yamada
- 申请人地址: JPX Tokyo CA LaJolla
- 专利权人: Japan Tobacco Inc.,Agouron Pharmaceuticals, Inc.
- 当前专利权人: Japan Tobacco Inc.,Agouron Pharmaceuticals, Inc.
- 当前专利权人地址: JPX Tokyo CA LaJolla
- 优先权: JPX7-248183 19950926
- 主分类号: C07C319/14
- IPC分类号: C07C319/14 ; C07C323/25 ; C07C323/42 ; C07D217/26 ; C07D263/14 ; C07D321/06 ; C07D413/04
摘要:
A method for producing an amide derivative of the formula [XV] ##STR1## wherein each symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof.The production method of the present invention is extremely easy and simple as compared to the conventional methods, and enables effective production of compound [XV] at high yields, which includes compound [XVI] having an HIV protease inhibitory action. In addition, the novel intermediates of the present invention are extremely useful as intermediates for producing not only the aforementioned compound [XVI] but also compounds useful as X-ray contrast media.
公开/授权文献
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