发明授权
- 专利标题： Flea protease proteins
- 专利标题（中）： 跳蚤蛋白酶蛋白
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申请号： US485443申请日： 1995-06-07
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公开(公告)号： US6146870A公开(公告)日： 2000-11-14
- 发明人: Robert B. Grieve , Keith E. Rushlow , Shirley Wu Hunter , Glenn R. Frank , Gary L. Stiegler
- 申请人： Robert B. Grieve , Keith E. Rushlow , Shirley Wu Hunter , Glenn R. Frank , Gary L. Stiegler
- 申请人地址： CO Ft. Collins
- 专利权人： Heska Corporation
- 当前专利权人： Heska Corporation
- 当前专利权人地址： CO Ft. Collins
- 主分类号： A61K35/00
- IPC分类号： A61K35/00 ; A61K39/00 ; C07K14/435 ; C07K16/18 ; C07K16/40 ; C12N9/48 ; C12N9/64 ; C12N15/12 ; C12P21/08 ; C12N9/50
摘要：
The present invention relates to flea serine protease and aminopeptidase proteins; to flea serine protease and aminopeptidase nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or aminopeptidase activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
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