发明授权
- 专利标题: Process for preparing phthalides
- 专利标题(中): 制备苯酞的方法
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申请号: US269773申请日: 1999-04-01
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公开(公告)号: US6147227A公开(公告)日: 2000-11-14
- 发明人: Klemens Massonne , Rainer Becker , Horst Neuhauser , Horst Zimmermann , Wolfgang Reif , Peter Cramers , Daniel Nardin
- 申请人: Klemens Massonne , Rainer Becker , Horst Neuhauser , Horst Zimmermann , Wolfgang Reif , Peter Cramers , Daniel Nardin
- 申请人地址: DEX Ludwigshafen
- 专利权人: BASF Aktiengesellschaft
- 当前专利权人: BASF Aktiengesellschaft
- 当前专利权人地址: DEX Ludwigshafen
- 优先权: DEX19640554 19961001
- 主分类号: C07D307/88
- IPC分类号: C07D307/88
摘要:
A process for preparing phthalides of the general formula I, ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen, C.sub.1-C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, by hydrogenating phthalic anhydrides of the general formula II, ##STR2## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each as defined above, with hydrogen in the presence of suspended catalysts of the Raney type in a hydrogenation apparatus by using a mixing apparatus to mix a liquid phase, which includes the catalyst and the phthalic anhydride used and resulting phthalide, and a gas phase, which includes the hydrogenating hydrogen, comprises using the mixing apparatus to introduce a mixing intensity of at least 50 W/l into the liquid phase.
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