- 专利标题： Use of aldosterone antagonists to inhibit myocardial fibrosis
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申请号： US281442申请日： 1999-03-29
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公开(公告)号： US6150347A公开(公告)日： 2000-11-21
- 发明人: Karl T. Weber
- 申请人： Karl T. Weber
- 申请人地址： MO Columbia
- 专利权人： The Curators of the University of Missouri
- 当前专利权人： The Curators of the University of Missouri
- 当前专利权人地址： MO Columbia
- 主分类号： A61K31/585
- IPC分类号： A61K31/585
摘要：
This invention discloses a method of using an aldosterone antagonist such as spironolactone, at a dosage which does not disrupt a patient's normal electrolyte and water-retention balance, to inhibit myocardial fibrosis, including left ventricular hypertrophy (LVH).
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