发明授权
- 专利标题: Sustained release compositions and a method of preparing pharmaceutical compositions
- 专利标题(中): 持续释放组合物和制备药物组合物的方法
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申请号: US370270申请日: 1999-08-09
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公开(公告)号: US6162467A公开(公告)日: 2000-12-19
- 发明人: Ronald Brown Miller , Stewart Thomas Leslie , Sandra Therese Antoinette Malkowska , Derek Allan Prater , Trevor John Knott , Joanne Heafield , Deborah Challis
- 申请人: Ronald Brown Miller , Stewart Thomas Leslie , Sandra Therese Antoinette Malkowska , Derek Allan Prater , Trevor John Knott , Joanne Heafield , Deborah Challis
- 申请人地址: LUX Luxembourg
- 专利权人: Euro-Celtique, S.A.
- 当前专利权人: Euro-Celtique, S.A.
- 当前专利权人地址: LUX Luxembourg
- 优先权: GBX9324045 19931123; GBX9403922 19940301; GBX9404544 19940309; GBX9404928 19940314; EPX94303128 19940429; EPX94304144 19940609; GBX9411842 19940614
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K9/16 ; A61K9/20 ; A61K9/26 ; A61K9/28 ; A61K9/48 ; A61K31/135 ; A61K31/485
摘要:
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form agglomerates, breaking the agglomerates to give controlled release particles and optionally continuing the mechanical working with the optional addition of a low percentage of the carrier or diluent.
公开/授权文献
- US4441575A Four-wheel vehicle drive system 公开/授权日:1984-04-10
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