发明授权
US6166186A Monoclonal antibody which binds to a human-Th2-specific protein and
hybridoma
有权
结合人Th2特异性蛋白质和杂交瘤的单克隆抗体
- 专利标题: Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma
- 专利标题(中): 结合人Th2特异性蛋白质和杂交瘤的单克隆抗体
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申请号: US480784申请日: 2000-01-10
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公开(公告)号: US6166186A公开(公告)日: 2000-12-26
- 发明人: Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Syoichi Takano
- 申请人: Kazuyuki Ogawa , Kazuya Tanaka , Kinya Nagata , Syoichi Takano
- 申请人地址: JPX
- 专利权人: BML, Inc.
- 当前专利权人: BML, Inc.
- 当前专利权人地址: JPX
- 优先权: JPX8-166793 19960605
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/47 ; C07K14/705 ; C07K16/28 ; C12N15/12 ; C12P21/08 ; C12N5/12 ; C07K16/44
摘要:
The present specification provides a means for specifying the condition and type of immune-related diseases on the basis of knowledge about the polarization of the distribution of helper T-cell subsets Th1 and Th2. More specifically, the gene (B19), specific only to the human Th2, is prepared by a subtraction method. A human-Th2-specific protein which the gene encodes is produced by recombinant methods, and a monoclonal antibody against the Th2-specific protein and a hybridoma which produces the monoclonal antibody is provided.
公开/授权文献
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