发明授权
US06171832B2 Process for the preparation cis-(1S,2R)-indanediol by direduction of 1,2-indanedione using trichosporon cutaneum
失效
通过使用trichosporon cutaneum引导1,2-茚满酮制备顺式 - （1S，2R） - 茚满二醇的方法
- 专利标题： Process for the preparation cis-(1S,2R)-indanediol by direduction of 1,2-indanedione using trichosporon cutaneum
- 专利标题（中）： 通过使用trichosporon cutaneum引导1,2-茚满酮制备顺式 - （1S，2R） - 茚满二醇的方法
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申请号： US09300344申请日： 1999-04-27
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公开(公告)号： US06171832B2公开(公告)日： 2001-01-09
- 发明人: Michael M. Chartrain , Norihiro Ikemoto , Anthony O. King
- 申请人： Michael M. Chartrain , Norihiro Ikemoto , Anthony O. King
- 主分类号： C12P722
- IPC分类号： C12P722
摘要：
A process for preparing cis-(1S,2R)-indanediol is disclosed. The process comprises (A) fermenting a culture medium containing a yeast strain selected from the group consisting of Trichosporon cutaneum MY 1506 (ATCC 74440) and mutants thereof and 1,2-indanedione to form cis-(1S,2R)-indanediol; and (B) recovering cis-(1S,2R)-indanediol from the culture medium. A process for preparing (1S)-amino-(2R)-indanol from the recovered cis-(1S,2R)-indanediol via the Ritter reaction is also disclosed.
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