- 专利标题： Method for preparing oxycodone
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申请号： US09419409申请日： 1999-10-15
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公开(公告)号： US06177567B1公开(公告)日： 2001-01-23
- 发明人: Fang-Ting Chiu , Young S. Lo
- 申请人： Fang-Ting Chiu , Young S. Lo
- 主分类号： C07D47100
- IPC分类号： C07D47100
摘要：
A method for the preparation of oxycodone, and salts thereof, from codeine comprising oxidation of codeine to codeinone, formation of an dienolsilyl ether congener of codeinone in strong amine base, oxidation of the dienolsilyl ether congener using peracetic acid, and hydrogenation of the resulting 14-hydroxycodeinone product.
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